Faculty Directory

White, Ian

White, Ian

Associate Chair and Director of Undergraduate Studies
Professor
Fischell Fellow
Fischell Department of Bioengineering
Brain and Behavior Institute
Robert E. Fischell Institute for Biomedical Devices
3112 A. James Clark Hall
Website(s):

EDUCATION

Ph.D., Stanford University, 2002

 

At the Amplified Molecular Sensors Lab, we aim to overcome the challenges that are preventing the realization of the next generation of biosensing and diagnostic systems. In particular, we emphasize the development and application of novel amplification strategies to add orders of magnitude improvement to chemical and biomolecular sensing, while at the same time improving the simplicity and usability of sensors and diagnostic systems.


At the Amplified Molecular Sensors Lab, we aim to overcome the challenges that are preventing the realization of the next generation of biosensing and diagnostic systems. In particular, we emphasize the development and application of novel amplification strategies to add orders of magnitude improvement to chemical and biomolecular sensing, while at the same time improving the simplicity and usability of sensors and diagnostic systems.

BIOE457: Biomedical Instrumentation

BIOE431: Fundamentals of Biosensing Techniques, Instrumentation, and Applications

  • Alessandra C. Zimmerman, Ian M. White, and Jason D. Kahn, "Nucleic acid-cleaving catalytic DNA for sensing and therapeutics, Talantain press, 2020.

  • Hieu T. Nguyen, Shweta Ganapati, David Watts, Imaly A. Nanayakkara, Philip DeShong, Ian M. White, A new trimodal phenotypic reporter of extended-spectrum beta-lactamase activity, ACS Infectious Disease, in press, 2019. DOI:10.1021/acsinfecdis.9b00138.

  • Imaly A. Nanayakkara and Ian M. White, Demonstration of a quantitative triplex LAMP assay with an improved probe-based readout for the detection of MRSA, Analyst, 144, 3878 - 3885, 2019. DOI:10.1039/C9AN00671K.

  • John P. Goertz, Kerry DeMella, Benjamin Thompson, Ian M. White, and Srinivasa Raghavan, Responsive capsules that enable hermetic encapsulation of contents and their thermally triggered burst-release, Materials Horizons, in press, 2019. DOI:10.1039/c9mh00309f.

  • Stephen M. Restaino and Ian M. White, A critical review of flexible and porous SERS sensors for analytical chemistry at the point-of-sample, Analytica Chimica Acta, 1060, 17-29, 2019, DOI:10.1016/j.aca.2018.11.057

  • John P. Goertz, Kenya Colvin, Andrew Lippe, John Daristotle, Peter Kofinas, and Ian M. White, Multi-Stage Chemical Heating for Instrument-Free Biosensing, ACS Applied Materials and Interfaces, 10, 33043–33048, 2018. DOI:10.1021/acsami.8b11611

  • John P. Goertz and Ian M. White, Phase-change partitions for thermal automation of multi-step reactions, Analytical Chemistry, 90, 3708–3713, 2018. DOI:10.1021/acs.analchem.7b05400.

  • Stephen M. Restaino and Ian M. White, Real-time multiplexed PCR using surface enhanced Raman spectroscopy in a thermoplastic chip, Lab on a Chip, 18, 832-839, 2018. DOI:10.1039/C7LC01227F.

  • John P. Goertz and Ian M. White, Peroxidyme-Amplified Radical Chain Reaction (PARCR): Nested Photochemical and Biochemical Positive Feedback, Angewandte Chemie, 56, 13411–13415, 2017. DOI:10.1002/anie.201706163.

  • Imaly A. Nanayakkara, Weidong Cao, and Ian M. White, Simplifying nucleic acid amplification from whole blood with direct PCR on chitosan microparticles, Analytical Chemistry, 89, 3773–3779, 2017. DOI:10.1021/acs.analchem.7b00274.

  • Adam G. Berger, Stephen M. Restaino, and Ian M. White, Vertical-flow paper SERS system for therapeutic drug monitoring of flucytosine in serum, Analytica Chimica Acta, 949C, 59-66, 2017. DOI:10.1016/j.aca.2016.10.035

  • Kunal R. Pandit, Imaly A. Nanayakkara, Weidong Cao, Srinivasa R. Raghavan, and Ian M. White, Capture and direct amplification of DNA on chitosan microparticles in a single PCR-optimal solution, Analytical Chemistry, 87, 11022-11029, 2015. DOI:10.1021/acs.analchem.5b03006

  • Kunal R. Pandit, Paul E. Rueger, Richard V. Calabrese, Srinivasa R. Raghavan, and Ian M. White, Assessment of surfactants for efficient droplet PCR in mineral oil using the pendant drop technique, Journal of Colloids and Surfaces B: Biointerfaces, 126, 489-495, 2015. DOI:10.1016/j.colsurfb.2015.01.001

  • Jeffrey M. Burke, Kunal Pandit, John P. Goertz, and Ian M. White, Fabrication of rigid microstructures with thiol-ene-based soft lithography for continuous-flow cell lysis, Biomicrofluidics, 8, 056503, 2014. DOI:10.1063/1.4897135.

  • Eric P. Hoppmann, Wei W. Yu, and Ian M. White, Multiplex detection of DNA targets using polymerase chain reaction (PCR) and paper surface enhanced Raman spectroscopy (SERS) chromatography, Applied Spectroscopy, 68, 909-915, 2014. DOI:10.1366/14-07451.

  • Jeffrey M. Burke, Rebecca E. Zubajlo, Elisabeth Smela, and Ian M. White, High-throughput particle separation and concentration using spiral inertial filtration, Biomicrofluidics, 8, 024105 2014. DOI:10.1063/1.4870399.

  • Jordan F. Betz, Wei W. Yu, Yi Cheng, Ian M. White, and Gary W. Rubloff, Simple SERS substrates: powerful, portable, and full of potential, Physical Chemistry Chemical Physics, 16, 2224-2239, 2014. DOI:10.1039/C3CP53560F.

  • Eric P. Hoppmann, Wei W. Yu, and Ian M. White, Inkjet-printed fluidic paper devices for chemical and biological analytics using surface enhanced Raman spectroscopy, Journal of Selected Topics in Quantum Electronics, 20, 7300510, 2014. DOI:10.1109/JSTQE.2013.2286076.

  • Soroush H. Yazdi, Kristen L. Giles, and Ian M. White, Multiplexed detection of DNA sequences using a competitive displacement assay in an microfluidic SERRS-based device, Analytical Chemistry, 85, 10605-10611, 2013. DOI:10.1021/ac402744z.

  • Eric P. Hoppmann, Wei W. Yu, and Ian M. White, Highly sensitive and flexible inkjet printed SERS sensors on paper, Methods, 63, 219-224, 2013. DOI:10.1016/j.ymeth.2013.07.010.

  • Wei W. Yu and Ian M. White, Chromatographic separation and detection of target analytes from complex samples using inkjet printed SERS substrates, Analyst, 138, 3679-3686 2013. DOI:10.1039/C3AN00673E.

  • Katayoon Saadin, Jeffrey M. Burke, Neerav P. Patel, Rebecca E. Zubajlo, and Ian M. White, Enrichment of tumor-initiating breast cancer cells within a mammosphere-culture microdevice, Biomedical Microdevices, 15, 645-655, 2013. DOI:10.1007/s10544-013-9755-y.

  • Wei W. Yu and Ian M. White, Inkjet-Printed Paper-Based SERS Dipsticks and Swabs for Trace Chemical Detection, Analyst, 138, 1020-1025, 2013. DOI:10.1039/C2AN36116G. (outside front cover)

  • Soroush H. Yazdi and Ian M. White, Multiplexed detection of aquaculture fungicides using a pump-free optofluidic SERS microsystem, Analyst, 138, 100-103, 2013. DOI:10.1039/C2AN36232E.

  • Soroush H. Yazdi and Ian M. White, Multiplexed detection of aquaculture fungicides using a pump-free optofluidic SERS microsystem, Analyst, 138, 100-103, 2013. DOI:10.1039/C2AN36232E.

  • Soroush H. Yazdi and Ian M. White, An Optofluidic SERS Microsystem for Sensitive and Repeatable On-Site Detection of Chemical Contaminants, Analytical Chemistry, 84, 7992-7998, 2012. DOI:10.1021/ac301747b.

  • Katayoon Saadin and Ian M. White, Breast cancer stem cell enrichment and isolation by mammosphere culture and its potential diagnostic applications, Expert Reviews of Molecular Diagnostics, 13, 49-60, 2013. DOI:10.1586/erm.12.117.

  • Ian M. White, Soroush H. Yazdi, and Wei W. Yu, Optofluidic SERS: synergizing photonics and microfluidics for chemical and biological analysis, Microfluidics and Nanofluidics, 12, 205-216, 2012. DOI:10.1007/s10404-012-0962-2

  • Wei W. Yu and Ian M. White, A simple filter-based approach to surface enhanced Raman spectroscopy for trace chemical detection, Analyst, 137, 168-173, 2012. DOI:10.1039/C2AN15947C.

  • Soroush H. Yazdi and Ian M. White, A nanoporous optofluidic microsystem for highly sensitive and repeatable SERS detection, Biomicrofluidics, 6, 014105, 2012. DOI:10.1063/1.3677369. (selected for publication in the Virtual Journal of Nanoscale Science and Technology and the Virtual Journal of Biological Physics Research)

  • Xudong Fan and Ian M. White, Optofluidic microsystems for chemical and biological analysis, Nature Photonics, 5, 591-597, 2011. DOI:10.1038/nphoton.2011.206.

  • I-Jane Chen and Ian M. White, High-sensitivity electrochemical enzyme-linked assay on a microfluidic interdigitated microelectrode, Biosensors and Bioelectronics, 26, 4375-4381, 2011. DOI:10.1016/j.bios.2011.04.044.

  • Wei W. Yu and Ian M. White, Inkjet Printed Surface Enhanced Raman Spectroscopy Array on Cellulose Paper, Analytical Chemistry 82, 9626-9630, 2010. DOI:10.1021/ac102475k.

  • Jikun Liu, Ian M. White, and Don L. DeVoe, Nanoparticle-Functionalized Porous Polymer Monolith Detection Elements for Surface-Enhanced Raman Scattering, Analytical Chemistry, 83, 2119-2124, 2011. DOI:10.1021/ac102932d.

Study Finds Race-based Disparities in Railroad Safety

Asian, Black, and Latino neighbornoods are more likely to be located near hazardous crossings.

At the White House: Professor Liangbing Hu Showcases More Sustainable, Steel-Strength “Super Wood”

Hu’s Super Wood Among 40 Great Innovations Offering Scalable Solutions to Societal Challenges

Alumnus Receives National Medal of Technology and Innovation

Biden recognizes Jeong H. Kim for advances in broadband optical systems, data communications, wireless.

A “Lint Roller” for Moon Dust

UMD researchers are creating a portable device that astronauts can use to get rid of clingy moon dust.

Erika Moore Receives NSF CAREER Award

Incoming BIOE faculty member Erika Moore receives prestigious NSF CAREER Award for immune system research.

24 Teams Present at BIOE Capstone Competition Including First BCE Students

On May 8, 2023, 24 teams presented novel designs at the BIOE Capstone Design Competition.

UMD Tapped to Lead Tier 1 University Transportation Center

Researchers awarded $10M to study use of autonomous vehicles, access and equity, and climate impacts.

Nearly 50-meter Laser Experiment Sets Record in Campus Hallway

Record set by group led by Professor Howard Milchberg

Jewell Named Associate Editor of Regenerative Medicine

Bioengineering Professor named to Nature Portfolio Journal editorial board.

Combating Metastatic Cancer Through Blood Draw

University of Maryland bioengineers develop a new technique to efficiently capture, gently release, and effectively scale up circulating tumor cells, a leading culprit in cancer spread.

Legacy of Racism Linked to Higher COVID-19 Death Rates

UMD researchers track health vulnerabilities among Black communities in Louisiana.

Jewell Named Controlled Release Society Fellow

BIOE Professor recognized for outstanding contributions to the field of delivery science and technology.

Maryland Engineering's Chris Jewell Appointed MPower Professor

Bioengineering professor one of eight UMD/UMB professors to receive UMD Strategic Partnership appointment.

Jewell Named BMES Fellow

BIOE Minta Martin Professor of Engineering Chris Jewell was named to the 2021 BMES Class of Fellows.

Everitt, Gaitan Granted 2020-2021 Fischell Fellowship

The department has named Fischell Fellows annually since 2003.

How tech can fill gaps in mental health care

$1.2M in NSF funding supports researchers’ work to connect patients, clinicians more effectively.

Secretary of State: 'Domestic Renewal' Needed Through Infrastructure Investments

Blinken emphasizes importance of spending at home to remain global leader in campus speech.

Ian White Receives Clark School’s Outstanding Faculty Service Award

BIOE associate professor recognized for efforts to promote high-quality instruction.

Four Clark School Faculty Receive CAREER Awards

Shelby Bensi, Gregg Duncan, Katrina Groth and Katharina Maisel are recipients of NSF CAREER grants.

He Lab Taps Machine Learning to Improve Cell-Based Medicine

Technology could one day be used to improve stem cell-based therapies as well as treatment options for diabetes and infertility.

White Lab Reviews Point-of-Care Diagnostics to Combat Pandemic

Micaela Everitt is first author of a review paper on point-of-care diagnostic technologies during a pandemic.

Plastic Alternative Made 100% of Wood

Study on strong, biodegradable and recyclable bioplastic published in Nature Sustainability.

Data-Driven Research, Pandemic Impact Highlighted at TRB

UMD researchers presented new findings, tools, and technologies, including a COVID-19 Impact Dashboard that leverages mobile device data.

Rejoining the Paris Accord: Scholars Respond

UMD's Deb Niemeier and other prominent researchers assess the new administration's course change on climate.

Waging War on Metastatic Cancer

BIOE Professor Xiaoming He and his research team take a new approach to understand why cancers spread.

Jewell Named 2021 Miegunyah Distinguished Visiting Fellow at the University of Melbourne

BIOE professor will collaborate on vaccine technologies at Peter Doherty Institute for Infection & Immunity 

UMD Launches Biocomputational Engineering Degree Program

New undergraduate degree merges biology, data science, and computer programming

BIOE Capstone Class Virtually Presents 24 Novel Projects

BIOE seniors present Capstone projects and celebrate winners virtually.

Better, Cheaper COVID-19 Tests

Compact, reusable system could quickly and cheaply test for multiple respiratory viruses.

New Data Shows States Not Meeting Reopening Benchmarks

University of Maryland’s SERA Metrics Track Readiness Indicators

BGSS Hosts Virtual "Research and Pajamas" Events

BGSS has transformed its "Research and Pizza" in person events to virtual "Research and Pajamas" gatherings.

Duncan, Maisel Recognized by American Lung Association

Bioengineering assistant professors awarded grants to advance lung health research.

'Wood' You Like Some Fresh Water?

New treatment for wood could make a membrane to extract fresh water.

Cooling Wood: An Eco-Friendly Building Material

UMD and Boulder engineers create strong, sustainable solution for passive cooling

Four BIOE Students Named NSF Graduate Research Fellows

Students recognized for research in immunoengineering, regenerative medicine, and more.

Spacecraft carrying Adomaitis thin film experiment docks with the International Space Station

The experiment will travel on the ISS for a year, exposing samples to the environment of low earth orbit.

UMD Celebrates Invention of Year Winners, Ventures, and Partnerships at 'Innovate Maryland'

An electric vehicle charger innovation takes home top honors for Invention of Year.

Maryland researchers develop computational approach to understanding brain dynamics

This paper published in PNAS develops a signal processing framework for extracting dynamic functional networks from neuronal data at unprecedented resolutions.

Hahn Receives NSF CAREER Award

NSF awards Hahn funding to research “white-box” autonomy in medical systems.

Clark School names Hamid Jafarkhani 2017 IHOF Inductee

Alumnus to join Innovation Hall of Fame roster in Nov. 27 ceremony.

President Obama names Michael Rotkowitz a recipient of the Presidential Early Career Award for Scientists and Engineers

The PECASE is the highest federal government honor for science and engineering professionals in the early stages of their careers.

White Named University of Maryland 2016 Faculty Advisor of the Year

BIOE associate chair and director of undergraduate studies honored during 21st Annual Undergraduate Studies Advising Conference.

Jewell Research Lab Explores New Therapies for Treatment of Juvenile Diabetes

Juvenile Diabetes Research Foundation awards Prof. Jewell $500,000 grant to study vaccine for diabetes.

BioE Capstone 2016: New Projects Focus on Improved Healthcare for Underserved Communities, Pediatric Patients, and More

Affordable RT-PCR for clinical diagnostics, fear mitigation device for pediatric MRIs tie for first place.

More Salt, More Power: UMD, ARL Researchers Building Better Batteries

A team of researchers at UMD, ARL, and colleagues have developed a battery that is at once safer, cheaper, more environmentally friendly, and more powerful - by adding a pinch of salt.

Four UMD Students Named 2016 Goldwater Scholars

UMD is one of five institutions with all four nominees named scholars

Leonard to be Honored for Cooperative Control Innovations

Alumna Naomi Leonard to be inducted into Innovation Hall of Fame on Nov. 9.

Sensing Drugged Driving: Fischell Researchers Receive SBIR for Roadside Drug Test

Diagnostic anSERS Inc. awarded $150,000 NSF grant to develop paper-based test to identify drivers under the influence of illegal drugs.

Forbes Receives APS 2015 George E. Duvall Shock Compression Science Award

Mechanical Engineering Visiting Professor Jerry Forbes Receives APS 2015 George E. Duvall Shock Compression Science Award.

UMD Clark School Highlights Disaster Resilience at Mpact Week

Five-day event focused on role of engineers in disaster prevention, mitigation, and response.

Clark School Alumnus Kub Honored for LED Material Innovation

Kub's Innovation Hall of Fame Induction Ceremony to take place Nov. 25.

Hydrophobically Modified Polymers Create “Cell Gels”

New technique could be used in tissue engineering, 3D cell culture.

Clark School Faculty Promotions Announced

Faculty promoted to full professor, associate professor with tenure.

BioE Capstone 2014: New Projects Focus on Cardiological Health, Surgical Tools and More

Students' inventions range from diagnostic devices to accident prevention products.

Galloway Contributes Expertise to CNA Corporation Military Advisory Board Report

CNA Corporation's "National Security and the Accelerating Risks of Climate Change" report describes climate change as a "threat multiplier."

UMD Entrepreneurship and Innovation Program Wins National Award for Excellence in Entrepreneurship Education

EIP takes first place in the Outstanding Specialty Entrepreneurship Program category.

White, Kofinas, and Chung Honored at Commencement

Bioengineering faculty and staff receive awards at December 22 ceremony.

NSF-Funded Project Provides Insight into Animal Behavior

Data gathering system could help protect endangered species.

UMD Launches Online Course for Transitioning Service Members and Veterans on Energy Problem Solving

Engineering course supported by Department of Defense will focus on design skills

Alumnus Krill to Be Honored for Revolutionary Naval Fleet Network Technology

Electrical engineering graduate Jerry Krill’s Cooperative Engagement Capability allowed Navy battle groups to act as one.

Diagnostic anSERS Takes 3rd and UMD Prize at Cupid's Cup Finals

Startup wins $10,000, plans to scale up manufacturing.

UMD and JHU Students Join Forces for Research Day

"Amplifying the Field" celebrates undergraduate contributions to biomedical research.

Diagnostic anSERS Heads to Cupid's Cup Finals

Printed sensors team to vie for $70,000 in April.

MIPS Program Awards $4.7 Million to Maryland University Researchers

Participating faculty help Maryland companies develop technology products.

Air Force Supports Study on Nanopaper for Electronics, Aircraft

Hu wins prestigious Air Force Young Investigator Award.

Chen Bioimaging Research Wins Prestigious NSF CAREER Award

Grant supports improvements to neural imaging and image-guided neurosurgery.

Diagnostic anSERS Pitches Dingman...and Wins!

BioE startup company wins funding for paper-based sensor product.

New Awards Support Research on Neonatal Ventilator Safety, Viral Diagnostics

Shapiro, White receive inaugural innovation grants from UM-CERSI.

Trento Funds Collaborative International Projects

Partnership will support joint research in solar power, cell-based systems and ultra low-power systems.

White's Research Wins Prestigious NSF CAREER Award

Inkjet-printed paper biosensors will reduce cost of diagnosing epidemic pathogens.

EIP Students Head to the White House

At "I Am an Entrepreneur" event, students learn from successful young business leaders.

Barbe Recognized by White House as Champion of Change

Champions are working to out-innovate, out-educate and out-build the rest of the world.

Inoue Joins BioE as Professor of the Practice

Canon U.S. Life Sciences senior fellow developing system for rapid diagnosis of disease.

Canon, Clark School Launch New Collaboration

Joint team to develop automated machine designed to expedite the diagnosis of infectious diseases.

UMD Cybersecurity Center Launch Event Set for Dec. 9

Event will feature keynote by Former Director of National Intelligence Mike McConnell.

How Did They Do It?

White Symposium to highlight dramatic uses of satellite technology.

Fair Showcases Undergrads' Summer Research

Students present their accomplishments after 11-week research program.

BioE Hosts Teachers in NSF-Sponsored Program

Summer workshop will improve K-12 engineering, math education.

Galloway Tapped by La. Governor

CEE professor, water expert to serve on advisory commission.

BioE Welcomes 3 New Faculty Members

Balaras, Muro and White arrive for Fall '08.

Inaugural Anderson Scholarship Awarded to Kirk

Madeline Kirk announced as first recipient of Anderson Scholarship in Aerospace Engineering.

Krizek Comments Now Available

Read Innovation Hall of Fame member's remarks on unique character of engineers.

Clark School Honors Innovator Laroia

Electrical engineering alumnus inducted into Innovation Hall of Fame for telecommunications inventions.

Clark School Accomplishments Spring 2002

A list of Clark school accomplishments for Spring 2002