Faculty Directory

Clyne, Alisa Morss

Clyne, Alisa Morss

Interim Department Chair
Professor
Fischell Fellow
Fischell Department of Bioengineering
Brain and Behavior Institute
Robert E. Fischell Institute for Biomedical Devices
4224 A. James Clark Hall

Ph.D., Medical and Mechanical Engineering, Harvard-MIT Division of Health Sciences and Technology
M.S., Mechanical Engineering, University of Cincinnati



B.S., Mechanical Engineering, Stanford University 
 
Dr. Clyne is director of the Vascular Kinetics Laboratory, which unravels the complexity of vascular diseases ranging from the very common (atherosclerosis, Alzheimer's disease) to the very rare (Niemann Pick). She is particularly interested in how altered blood flow (e.g., during exercise or at an arterial bifurcation) and altered blood metabolites (e.g., high glucose in diabetes) contribute to vascular disease. The laboratory uses 3D in vitro systems, computational models, and animal and human studies to discover fundamental biological mechanisms, which then enable innovative vascular disease therapies.
 
Dr. Clyne is a fellow of the American Society of Mechanical Engineering  (ASME), Biomedical Engineering Society (BMES), American Heart Association (AHA), and the American Institute for Medical and Biological Engineering (AIMBE). She received the NSF CAREER award in 2008, an AHA National Scientist Development Grant in 2010, the BMES-CMBE Rising Star award in 2011, the Association for Women in Science Elizabeth Bingham Mentoring Award in 2017, the University of Maryland Faculty Service Award and Poole & Kent Teaching Award in 2025, a Fulbright Distinguished Scholar Award in 2025, and the ASME Van C. Mow Medal in 2026. 
 
Her research and educational innovations are funded by NIH, NSF, AHA, and the Department of Education.

ENES100: Introduction to Engineering Design

BIOE331: Biofluid Mechanics

BIOE416: Cardiovascular Engineering

BIOE Celebrates Five Award Recipients at Ninth Annual 2026 EPIC Retreat

Five members of BIOE were recognized for research, service, and contributions to the department.

UMD Bioengineering Undergraduate Program Continues Strong National Standing

Department highlights cross-campus partnerships and hands-on student innovation

Grand Challenges 2.0: Engineers Partner to Unlock Solutions

Seven of 11 collaborative projects include contributions from engineering

Alisa Morss Clyne Named Interim Chair of UMD Bioengineering

Alisa Morss Clyne will serve as interim chair of UMD Bioengineering starting Aug. 1, 2026.

Cholesterol Found to Play Key Role in Protecting the Blood-Brain Barrier

Clyne Lab uncovers how cholesterol helps maintain the brain’s protective barrier.

BIOE Students Earn Top Honors for Health Innovation at 2025 Capstone Expo

BIOE and BCE students showcased innovative health tech solutions at the 2025 Capstone Design Expo.

Clyne Discusses Gene-Exercise Connection in Alzheimer’s Research on Podcast

Clyne discusses how the APOE4 gene may affect the brain’s response to exercise on a new podcast.

Guiding the Future Direction in Modeling the Blood-Brain Barrier for Improved Brain Health

BIOE researchers publish innovative research in blood-brain barrier modeling.

Goldberg Appointed Associate Chair of Diversity, Equity, Inclusion, and Belonging in BIOE

This Fall, Senior Lecturer Deborah Goldberg will lead Diversity, Equity, Inclusion, and Belonging in BIOE.

Agents of Positive Change: Highlighting Women Maryland Engineers

In celebration of Women's History Month, we highlight some of the important contributions of women engineers within our campus community.

24 Teams Present at BIOE Capstone Competition Including First BCE Students

On May 8, 2023, 24 teams presented novel designs at the BIOE Capstone Design Competition.

Five BIOE Students & Alumni Named NSF Graduate Research Fellows

The NSF Graduate Research Fellowship Program (GRFP) was established to ensure the vitality and diversity of the scientific and engineering workforce of the United States.

Recent Bioengineering Graduate Awarded National Mitchell Scholarship

Neelesh Mupparapu (B.S. bioengineering '22) named one of 12 winners to pursue graduate study in Ireland

Do Suddenly Self-Centered Brain Cells Promote Disease?

NSF Award Funds UMD Alzheimer’s Research Into Brain Glucose Metabolism

$7.9 Million in NIH Awards Propel UMD Aging Research

New multidisciplinary collaborations take on challenges like Alzheimer’s disease prevention.

Celebrating 14 Participants of 2021 BIOE REU Program

The BIOE REU program promotes collaboration between UMD and the FDA, making it unlike any other in the country

Maisel to Investigate Little-Known Organ in the Body

Dr. Katharina Maisel was awarded a $1.8 million NIH NIGMS grant to study the interstitium and lymphatics.

Maryland Graduate Engineering Ranked #10 Public in the Nation

From extreme batteries to windows made from wood, Clark School’s trendsetting work ranks it among the country’s Top 10 public engineering schools for the 3rd consecutive year.

One Size Does Not Fit All

To advance inclusive medical therapies and diversity in fundamental science, one Maryland engineer leads by example.

BBI Awards Seed Grants to Six Interdisciplinary Projects

Funded teams feature UMD faculty from 15 academic departments and six centers and institutes

Clyne Named BIOE Associate Chair, Diversity, Equity & Inclusion

Role will support efforts to enhance diversity within the department and in the STEM fields at large.

BIOE Capstone Class Virtually Presents 24 Novel Projects

BIOE seniors present Capstone projects and celebrate winners virtually.

Clyne, Jewell Inducted into AIMBE College of Fellows

BIOE faculty awarded one of the highest professional distinctions accorded to a medical/biological engineer.

Clyne, Maisel to Join BIOE Faculty in 2019

Associate, assistant professors bring expertise in endothelial cell biology, mucosal drug delivery.